Review on CRISPR-CAS system of genomic editing. Targeting cancer cell metabolism: Just like the Crabtree effect in S.cerevisiae, Cancer cells have unusually high glycolytic flux as well. Even when there is oxygen available, cancer cells choose to ferment, to accumulate lactic acid. This is known as Warburg effect. I wonder if the excreted lactic acid stresses cancer cells, just as acetic acid is toxic to S.cerevisiae ? … Continue reading Research News – 2